Anemia of prematurity

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Teza de doctorat prin cercetarea efectuat i propune s analizeze aspecte legate de tratamentul anemiei de prematuritate cu rHuEPO comparativ cu transfuziile de mas eritrocitar, evoluia comparativ a patologiei asociate prematuritii: sindromul de detres respiratorie, bronhodisplazia pulmonar, retinopatia de prematuritate, hemoragiile intraventriculare, leucomalacii, enterocolita ulceronecrotic, precum i scderea numrului de transfuzii i anemia of prematurity a riscurilor i complicaiilor acestora. Astfel s-au cercetat clinic i paraclinic valorile n dinamic a prametrilor Hb, Ht, ASTRUPimagistic: ecografiile transfontanelare n dinamic, n ziua 1, 3, 7, 14, 30, i la externare, radiografic, dou grupuri comparabile de prematuri cu greutate foarte anemia of prematurity la natere subgunul care primete tratament cu rHuEPO cel de-al doilea primete transfuzii de mas eritrocitar ME. Rezultatele statistice arat c pentru atingerea unor valori ale parametrilor hematologici similari, grupul tratat cu rEpo a avut o evoluie mai bun n sensul reducerii incidenei i gravitii hemoragiilor intraventriculare, o reducere a incidenei retinopatiei de prematuritate i a gravitii, prelungirea timpului de apariie a nivelului minim de anemia of prematurity nadirreducerea necesitii transfuziilor numr sczut semnificativ.

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Pathophysiology In the normally developing retina, there are no retinal vessels until about 16 weeks of gestation. Retinal vascularization begins at the optic nerve at 16 weeks of gestational age GA and is completed by 40 weeks GA. Preterm infants have incompletely vascularized retinas. ROP is a biphasic disease consisting of an initial phase of vessel growth cessation and loss followed by a second phase of anemia of prematurity proliferation.

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Diagnosticul anemiei În prezent, criteriile de diagnostic al anemiei la nou-nascut nu sunt foarte bine stabilite si fundamentate stiintific. Detectarea anemiei semnificative clinic este, în prezent, un domeniu de cercetari active. Tabelul anexat ilustreaza ghidul pentru transfuzii la nou-nascutii prematuri, folosit în Clinica de Terapie Intensiva Neonatala a Universitatii Iowa. Transfuziile nu trebuie doar sa înlocuiasca pierderile iatrogene de sânge.

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E-mail: moc. This article has been cited by other articles in PMC. Abstract AIM: Our study aims to make a comparison between the effects of milking of umbilical cord versus delayed cord clamping on Hemoglobin level at 6 weeks from delivery among term neonates and which method is more beneficial for them. Participants were randomised into 2 groups; Group 1: women were assigned to delay cord clamping; Group 2: women were assigned anemia of prematurity milking of the umbilical cord 5 times before cutting.

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