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Numeroasele studii efectuate au aratat ca mutatiile genelor BRCA1 si BRCA2 care afecteaza linia germinala sunt responsabile breast cancer genetic markers marea majoritate a cancerelor ereditare de san si ovar1;7. Desi persoanele cu HBOC mostenesc o alela BRCA1 sau BRCA2 defectuoasa de la unul dintre parinti, acestia prezinta o a doua alela functionala; in cazul in care si cea de-a doua alela devine nefunctionala  se dezvolta procesul neoplazic, prin acumularea de mutatii aditionale. Aceste tipuri de mutatii au fost identificate predominant la evreii Ashkenazi din Europa de Estcanadienii francezi si la islandezi1.

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Subscribe What is EndoPredict? EndoPredict is a 2nd generation multi-gene breast cancer recurrence test for pre- or postmenopausal women newly diagnosed with early-stage breast cancer. Created for the breast cancer genetic markers of highly accurate assessment of 5 to year risk of distant recurrence of the disease EndoPredict combines into an unique indicator EPClin score gene expression with clinically pathological features providing outstanding prognostic performance that will ensure the healthcare professional that chemotherapy is or is not required to accompany endocrine treatment.

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Pentru bărbaţii cu mutaţii BRCA2 riscul cumulat de cancer mamar până la vârsta de 80 ani a fost estimat la 6. Cancerul ovarian prezintă un fenotip histologic distinct la această categorie de paciente, înregistrându-se în principal tumori seroase sau endometrioide de grad înalt1.

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The aim of current work is to update the information about the clinical practice implementation of molecular markers used for diagnosis, prognosis and individual therapy in women breast cancer. Material and method.

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Departamentul lui nu va găsi un tratament pentru cancerul de sân. His department's not going to find the cure for breast cancer. Știi, cancerul de sân, minele antipersonal.

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Пока октопауки не проявляли излишней агрессивности, но тем не менее приступили к подготовке войны с людьми. И хотя военные действия они начнут только в случае явной угрозы жизни их колонии, глубокие познания октопауков в биологии делают исход войны предрешенным. Правда, еще не ясно, как отреагируют люди на первые тяжелые потери. Вероятно, война быстро окончится, и через некоторое время оба уцелевших сообщества смогут достичь равновесного состояния.

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