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Image: © Nicolle Rager Fuller, National Science Foundation A blood type that can turn blood transfusions deadly has proven a perplexing mystery for 60 years. Now researchers have finally identified the secret behind the blood type known as "Vel," findings that could help make blood safer for hundreds of thousands of people worldwide. The mystery began inwhen cancer genetic blood test year-old woman in New York, sick with colon cancerreceived a blood transfusion and unexpectedly suffered from a severe and potentially fatal rejection of the blood. Investigators referred to her, using her last name, simply as Patient Vel.

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Radiol Oncol ; 53 3 :09 Currently, several predictive or prognostic genetic alterations have been identified and are used in clinical practice. BRAF VE mutations are rare and occur mostly in tumors located in the ascending colon in elderly female patients. BRAF is instrumental in establishing prognosis: survival is shorter by months in BRAF-mutant patients, and BRAF may be a negative prognostic factor for patients who undergo hepatic or pulmonary metastasectomy.

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Accepted Apr Copyright © The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work cancer genetic blood test properly cited. This article has been cited by other articles in PMC.

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