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Se cunosc peste de tulpini de HPV si nu toate dau aceeasi simptomatologie. Virusul papilloma e atras de epiteliul scuamos ce se regaseste la suprafata pielii si a mucoaselor vaginala, anala, bucala. Aproximativ 60 de tulpini de HPV sunt responsabile de aparitia negilor comuni papiloame, condiloame pe suprafata pielii care sunt tumori ne-canceroase. Alte 40 de tipuri adera doar condyloma acuminata lsil mucoase unde epiteliul e umed si poarta numele de tulpini anogenitale.

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Metodele de testare pentru HPV cunoscute pina in prezent prezinta dezavantaje care nu trebuie neglijate: detecteaza un numar relativ mic de tipuri condyloma acuminata lsil HPV comparativ cu cele existente 37 de tipuri, fata de cele peste de tipuri cunoscutese aplica doar pentru prelevate cervicale in mediu lichid excluzind astfel leziunile anale, oro-faringiene, conjunctivale, epidermice, laringealeau sensibilitate limitata pentru unele tipuri, limita de detectie ajunge si la de copii ADN, ceea ce sugereaza un numar relativ mare de cazuri fals negative, datorate fie recoltarii unui numar mic de celule, fie infectarii cu virus a unui numar mic de celule. Laboratoarele synlab utilizeaza acum o metoda de testare a HPV care exclude toate aceste inconveniente. Virusurile Papilloma sint virusuri ADN din grupul papovavirusuri.

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Capsida papilomavirusurilor Fig. Incidena infeciei cu HPV pe categorii de vrst Grosimea nveliului proteic este de aproximativ 8nm i nu prezint un nveli lipidic, ca Rezultatele studiului relev faptul c infecia cu majoritatea ADN-virusurilor.

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