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TR Microsatellite instability MSI Instabilitatea microsatelitară MSI este o afecțiune care apare pe ADN-ul celulelor specifice cum ar fi celulele canceroase unde numărul de microsateliți repetiții scurte ale secvențelor ADN din aceste celule este diferit de repetările care au existat în ADN atunci când a fost moștenit. Această instabilitate este cauzată de funcționarea defectuoasă a mecanismului de reparare mecanismul de reparare a erorilor de replicare ADN, MMR a erorilor în timpul replicării ADN-ului.

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