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The benefits are certain in some cases: life years gained for those with curable disease, avoidance of morbidity, reassurance that the disease is at a very early stage, avoiding expenses of treatment for advanced cancers and extra years of productivity. But screening genetic cancer blood also have disadvantages, so a balanced decision must be made, with the help of clinical randomized trials.

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And he was surprised by what he learned. And so it goes in the fledgling genome field.

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