Helminths host immune response

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Se estimează că peste un miliard de helminths host immune response sunt purtători de Trichuris pe toată planeta, inclusiv mai mult de de milioane de copii de vârstă preșcolară și mai mult de de milioane de copii școlarizați de ani [25] [26]. Grupa de vârstă cea mai afectată este ani, dar este întâlnit și la copii mai mici. Cel puțin 27 milioane copii de vârstă școlară sunt infectați în Africa Subsahariană, 36 milioane în India, 42 milioane în China, 39 milioane în America Latină și Caraibe [22].

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Comentarii The type 2 immune response that develops during helminths host immune response disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite.

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Now fully revised and updated, Mims' clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember. Learn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the 'bug parade' into a clinical context. Effectively review for problem-based courses with the help of chapter introductions and 'Lessons in Microbiology' text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools.