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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3]. Structura HPV women.

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Posts: Înscris: Dar se pare ca nu au fost citite. Nu ma deranjeaza sa reiau unele uinformatii. Deci: Vaccinul are denumirea comerciala Silgard, solutie injectabila intr-o seringa preumpluta.

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Арчи даже не стал подтверждать то, что Синий Доктор рассказывала Николь о принципах терминационной политики. - Жутковато, не правда. - Эпонина скривилась и продолжила: - А Николь говорила, что Синий Доктор несколько раз ей все повторила, а потом она сама пересказала то же самое на английском в присутствии Синего Доктора, чтобы удостовериться в том, что правильно все поняла. - Ничего сложного, - Макс выдавил улыбку, - даже для фермера.