Neuroendocrine cancer of the lung

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Distribuie pe: DESCRIERE Respiratory cytopathology is indispensable in the workup of patients suspected of having lung cancer requiring cytologic evaluation and is used increasingly in immunocompromised patients for the identification of infectious diseases. Currently, there is no single text devoted exclusively to Pulmonary Cytology. Color Atlas of Pulmonary Cytopathology is the only text to include, under one cover, up-to-date information on every aspect of Respiratory Cytopathology.

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As a result, the medical management has been rigorously quantified in terms of clinical-histological characteristics and the invasive tumour stage, the degree of mediastinal lymph node extension and the presence of distant metastases determined with the TNM staging system that is recognised globally The x-ray examination reveals only pathological mediastinal lymph nodes that cause changes of mediastinal margins and the pleural reflection lines. The disadvantage of the traditional x-ray examination is the impossibility to identify the lymph nodes situated within the mediastinum. Also if the lymph nodes are hidden behind other tumour masses existing in the mediastinum, they cannot be discovered at the x-ray examination, which offers little information about the mediastinal structure: vessels, lung, pericardium, pleura, and thoracic wall. Due to the possibility to reveal all groups of pathological mediastinal lymph nodes, computed tomography is the first choice examination for the diagnosis of mediastinal adenopathies.

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The symptoms of neuroendocrine tumours depend on the location of the primary tumour. Simptomele tumorilor neuroendocrine depind de localizarea tumorii primare. Cytokines are soluble molecules. Citokinele sunt molecule solubile, care realizează comunicarea bidirecţională între celulele neuroendocrine şi celulele imunocompetente.

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MATERIALS AND METHODS: Imaging studies of 22 patients 12 men, mean age 60 years with histopathologically confirmed diagnosis, evaluated in the authors's institution during the last five years were retrospectively reviewed by two radiologists, with findings being consensually described focusing on changes observed at computed tomography. Only one typical carcinoid presented the characteristic appearance of central endobronchial nodule with distal pulmonary atelectasis, while the others were pulmonary nodules or masses.

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Aceasta implica injectarea pacientilor cu material radioactiv care se ataseaza la celula maligna si apoi absoarbe si distruge celula cu pagube minime la alte tesuturi. Noul tratament este rodul a trei ani de colaborare intre Hadassah si Centrul de Cercetari Nucleare Soreg.