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Articole de sinteza Jurnalul de Chirurgie, Iasi,Vol. Iniţial s-a vrut a fi un marker serologic specific pentru carcinomul colorectal care să pună precoce diagnosticul la pacienţii asimptomatici, dar curând s-a demonstrat că niveluri serice ridicate apar şi în alte cancere, în afecţiuni non- maligne intestinale şi chiar la indivizi normali atunci când îşi schimbă brusc obiceiurile de fumat sau băut. Valorile ACE ridicate la pacienţii cu cancer colorectal depind şi de prezenţa vaselor sangvine peritumorale, de reactia inflamatorie imună la celulele tumorale şi de starea celulelor Kupfer hepatice care deţin receptori capabili de-a lega această glicoproteină şi a-i favoriza clearance-ul din circulaţie [4].

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Note most institutions surgical sub-specialties develop their own bundles to address local issues by selecting a sub-set of the menu of elements listed Organ space infections, as they pertain to CRS, include abdominopelvic abscesses, anastomotic leak, and enteric fistulae. Although current mortality rates are much improved, organ space infections are still a very severe complication.

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